Holistic B6, B12 & Folate Methylated – For Optimal Methylation and Energy-Balanced Health
B6 B12 Folate Methylated by Holistic is an advanced dietary supplement designed to support the body’s methylation processes – a vital function for gene expression, detoxification, and nervous system well-being. The product contains four carefully selected forms of B vitamins in their most bioactive and easily absorbed forms, including the methyl group donor trimethylglycine (TMG), which supports the body’s natural methylation.
Key Features of B6 B12 Folate Methylated
-
Four selected and active forms of B vitamins
-
Contains the methyl group donor trimethylglycine (TMG)
-
Contributes to the normal function of the immune system
-
Helps reduce tiredness and fatigue
-
Supports normal psychological function and the nervous system
-
Promotes normal homocysteine metabolism
What is methylation and why is it important?
Methylation is a biochemical process in which methyl groups are transferred to DNA, proteins, and enzymes – impacting everything from detoxification and hormone balance to gene regulation and energy metabolism. For this process to function optimally, the body requires access to methylated forms of vitamins B6, B12, and folate, along with supportive nutrients like TMG (trimethylglycine).
Who is B6 B12 Folate Methylated 60 capsules by Holistic suitable for?
This supplement is especially suitable for those who:
-
Want to support mental clarity and focus
-
Experience fatigue or low energy levels
-
Seek help in balancing homocysteine levels
-
Want to support optimal detoxification and cellular function
Dosage
1 capsule twice daily. The recommended daily dose should not be exceeded.
Contraindications and side effects
Do not use if you have a genetic sensitivity to methylated vitamins.
Nutritional content per 2 capsules
| Ingredient | Amount | % DRI* |
|---|---|---|
| Trimethylglycine | 200 mg | * |
| Vitamin B6 | 25 mg | 1,786% |
| Folic acid | 500 μg | 250% |
| Vitamin B12 | 1,000 μg | 40,000% |
*Daily Reference Intake not established
Ingredients in B6 B12 Folate Methylated 60 capsules Holistic
Filler (rice flour), trimethylglycine, capsule shell (pullulan), vitamin B12 (methylcobalamin, 5’-deoxyadenosylcobalamin), vitamin B6 (pyridoxal-5’-phosphate), anti-caking agents (MCT oil from coconut, silicon dioxide), folic acid (Quatrefolic®).
*NL-BIO-01
Storage
Store in a dry place and out of reach of small children.
Other information
Food supplements should not be used as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important.
-
What does it mean that the vitamins are in “methylated form”?
Methylated vitamins are already in their active form, which means the body can use them directly without needing to convert them first. This is especially important for individuals with impaired methylation capacity, such as those with MTHFR gene variations. -
Why is trimethylglycine (TMG) included in the product?
TMG acts as a methyl group donor and supports the body’s methylation processes. It helps lower homocysteine levels and promotes healthy cellular function and detoxification. -
Who may benefit from taking Holistic B6 B12 Folate Methylated?
People experiencing fatigue, brain fog, low mood, or those with an increased need for methylation support – for example due to stress, long-term medication use, or genetic variations – may benefit greatly from this supplement. -
Can this product be combined with other supplements?
Yes, Holistic B6 B12 Folate Methylated can be effectively combined with other supplements that support the nervous system, such as magnesium, omega-3s, or adaptogens. Among biohackers, it’s also common to combine it with NAD+, creatine, or methylene blue. -
How does the product affect homocysteine levels in the body?
The active forms of vitamin B6, B12, and folate contribute to the normal metabolism of homocysteine, which is important for cardiovascular and brain health. Elevated homocysteine levels are linked to increased risk of inflammation and accelerated aging.
Biohacking & Longevity Perspective
In the world of biohacking, methylation is a key area for those aiming to optimize their biological age, enhance cognition, and protect against chronic inflammation. By supplying the body with active, methylated B vitamins, you provide essential tools to improve detoxification pathways, stabilize mood, and shield the brain from oxidative stress. Holistic B6 B12 Folate Methylated is therefore a natural choice for anyone serious about long-term health and performance.
